In this episode, Kim Isenberg speaks with Sven Breuner from VAST Data about the infrastructure behind modern AI systems — from GPU utilization and storage architecture to HPC, inference, data movement, and the emerging concept of AI factories.

Kim Isenberg sits down with NVIDIA’s Sam Stanwyck at ISC to discuss one of the most misunderstood frontiers in technology: quantum computing.

In this exclusive Superintelligence interview, Kim Isenberg and Peter Thum sit down with Akshay Kothari, Co-Founder of Notion, to discuss how Notion is evolving from a notes and productivity app into an agent-first workspace.

In this exclusive interview from Google I/O, I speak with Omar Sanseviero and Paige Bailey from Google DeepMind about the rapidly evolving AI landscape. We discuss the rise of local models, the growing importance of open source and open models, the role of developer communities, and how global competition — especially from China — is shaping the next phase of artificial intelligence.

Superintelligence Editor-in-Chief Kim Isenberg speaks with Zeev Farbman, CEO and co-founder of Lightricks/LTX, about the future of AI video, open foundation models, and local creative workflows.

Superintelligence Editor-in-Chief Kim sits down with SkipUp co-founders Dheer and Sasha to unpack why scheduling is still fundamentally broken in 2026 and how their AI agent is replacing the entire back-and-forth

LLMs predict the next word. LQMs predict the physical world. In this episode, Kim sits down with Nadia Harhen, General Manager of AI Simulation at SandboxAQ — a company that spun out of Google's Moonshot Factory, raised over $950 million, and counts NVIDIA and Google among its investors. Nadia explains what Large Quantitative Models (LQMs) are, how they differ from the LLMs we all know, and why they could be the key to inventing new drugs, designing next-generation batteries, and tackling problems like rare genetic diseases and environmental waste. We talk about her journey from bench scientist at Johnson & Johnson to clearing cutting-edge AI medical devices to leading one of the most ambitious AI simulation teams in the world. We discuss SandboxAQ's work with Aramco on turning waste into valuable materials, why no AI-designed drug has passed Phase II clinical trials yet, and what breakthroughs she expects in the next five years. If you think AI is just about chatbots and text generation, this episode will change your mind.

NVIDIA’s Kari Briski joins Kim Isenberg live from GTC 2026 to break down Nemotron 3 Super — a 120B parameter model with a hybrid Mamba-2/Transformer/MoE architecture, 1M token context, and 5x throughput gains. They go deep on what makes it different, why NVIDIA released the full training recipe, and what the new Nemotron Coalition signals about where enterprise AI is heading.