OpenAI’s ChatGPT-5 released

Dear Readers,

Hardly a day goes by without new headlines about artificial intelligence – but today is different. GPT-5 is here, and what we are experiencing is not just an upgrade, but a quantum leap: a system that recognizes when it needs to think. This is no longer science fiction – it is the moment when tools become real partners. What does this mean for programmers, entrepreneurs, and creatives? For you?

In this issue, we dive deep: How is GPT-5 changing the relationship between humans and machines – and why is the entire tech world already talking about “autonomous workflows on demand”? Also: a groundbreaking study on psilocybin as a potential anti-aging agent, new tools for personalized longevity therapies, and a protein that makes cells younger. If you think the 21st century has yet to reach its turning point, read on.

In Today’s Issue:

All the best,

The AI world is at a turning point: OpenAI officially released GPT-5 on August 7, 2025, and this system exceeds all expectations. After months of speculation, the new flagship model is finally available – and it changes everything we thought we knew about AI systems.

What makes GPT-5 so special? It is a unified system with integrated thinking that automatically recognizes when quick answers are sufficient and when more complex reasoning is required. The numbers speak for themselves: 94.6% accuracy on mathematical AIME problems, 74.9% on real-world coding tasks, and a dramatic 45% reduction in hallucinations compared to GPT-4o.

Particularly impressive: GPT-5 can create complete, aesthetically pleasing websites, apps, and games with just one prompt – including parallax scrolling and responsive design. For the AI community, this means the transition from tool juggling to an intelligent partner that independently handles complex, multi-step workflows.

What will this revolution mean for our industry? Will we all soon become AI conductors instead of developers?

Why it matters: GPT-5 marks the transition from specialized AI tools to a universal intelligence partner that could exponentially increase productivity in all areas. This development could revolutionize the world of work similarly to how the internet did in the 90s.

Sources:

🔗  https://www.axios.com/2025/07/24/openai-gpt-5-august-2025

🔗  https://openai.com/index/introducing-gpt-5/

🔗  https://medium.com/artificial-corner/gpt-5-launch-is-expected-in-august-2025-heres-everything-we-know-so-far-cb92617e318b

🔗  https://botpress.com/blog/everything-you-should-know-about-gpt-5

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A groundbreaking Emory study shows that psilocin, the active ingredient in psilocybin mushrooms, extends the lifespan of human skin and lung cells by over 50%. The research demonstrates systemic anti-aging effects for the first time through the reduction of oxidative stress, improved DNA repair, and telomere protection. This discovery could revolutionize anti-aging therapies, as most cells in the body express serotonin receptors and psilocybin improves not only longevity but also quality of life in old age.

Artificial intelligence is transforming aging research and enabling personalized treatments for healthier, longer lives. New AI systems can predict individual aging patterns, calculate optimal interventions, and analyze biomarkers in real time. This technological revolution promises tailored longevity strategies based on genetic, epigenetic, and lifestyle factors—a paradigm shift from universal to highly personalized anti-aging protocols.

Researchers at the University of Ulm have identified the protein Cdc42 as a key factor in cellular decline. The experimental inhibitor CASIN rejuvenated the immune system in mice, improved bone healing, and extended lifespan. Critical: Unlike Silicon Valley “immortality” visions (e.g., cryonics), this serious geromedical research aims at quality of life, not eternity. A start-up is now working on human therapies—a milestone for clinical age treatment.

Working at the intersection of AI and human longevity? We’re inviting researchers and innovators to submit their work to be featured in Superintelligence, the leading AI newsletter with 200k+ readers.

Whether you’re using AI to extend lifespan, improve healthspan, or accelerate biomedical breakthroughs, email your arXiv.org link or a summary to [email protected] with the subject line “Longevity Submission”. If selected, we’ll contact you for a potential feature.

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