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Dear Readers,
It's no longer a coincidence - it's a turning point. What we are experiencing today is not just a feature update, it is a paradigm shift: artificial intelligence is beginning to speak. And in the literal sense. With Claude 's new voice function, Anthropic is not just launching an assistance tool on the market, but a promise - that technology will no longer serve us, but enter into a real dialog with us.
In the Longevity section, we see how data medicine, epigenetics and pharmacology are working towards one goal: a longer, healthier life. And here too: AI is not just a tool, but a guide. It analyzes, recognizes patterns and opens up healing paths that humans would not even have seen on their own.
All this shows: We are at the beginning of a decade in which three forces are combining - language, computation and biology. Anyone who listens to Claude today is actually listening to the future
In Today’s Issue:
Claude Finds Its Voice — A Hands-Free Future for AI Assistants
Claude 4 Works a Full Shift — Research, Code, and Project Management
Intelligence Explosion? Not Without More Compute
Open-Source Med Models Raise the Bar for Clinical AI
And more AI goodness…
All the best,
Claude gets a voice!
The TLDR
Anthropic has rolled out voice functionality for Claude, transforming it into a hands-free, conversational assistant capable of managing tasks, reading emails, and taking notes through natural speech. With five voices, context awareness, and smart integration into calendars and documents, Claude moves a step closer to becoming a true multimodal AI companion.
With a simple app update, Anthropic is changing the way we talk to AI - literally. Claude, the well-known AI assistant, now has a voice function that enables real dialog: listening, speaking, understanding - all in natural language, without any typing.
Users can choose from five unique voices, switch between text and voice input and link Claude directly to calendars, emails or documents. Especially for power users with Claude Pro or Max, this means voice-controlled organization of everyday life without lifting a finger. Whether summarizing meetings, reading out emails or creating spontaneous notes - Claude responds promptly and contextually.
The special feature: The AI recognizes the course of conversations and automatically adds visual notes - a real step forward towards multimodal AI usage. This means that Claude is growing into a role that was previously a dream of the future: an assistance system that actively thinks for itself.
Why it matters: This voice function marks the transition from passive to truly interactive AI systems. It makes access to AI more inclusive - and opens up completely new fields of application in everyday life, work and education.
Sources:
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In The News
Claude 4 Works the Entire Workday So You Don’t Have To
Claude 4 is stepping into the role of a true AI coworker—handling research, coding, and project management with ease. In a live demo, Anthropic’s team shows how Claude integrates with tools like Google Workspace and Asana, automates development in Claude Code, and delivers detailed, structured output. Whether you're drafting reports or managing sprints, Claude is now built to carry your workflow from start to finish.
Is the Intelligence Explosion Stalled by Compute Limits?
New research from @noshpesoj and @uchicagoxlab suggests that even if we see rapid algorithmic progress, a true intelligence explosion by 2027 may be constrained by hardware bottlenecks. The study, featured in this week’s Gradient Update, raises critical questions about whether compute availability can keep pace with accelerating AI capabilities.
Open-Source Med AI Models Hit New Milestone
New 4B multimodal and 27B text-reasoning models show strong performance in medical image and text understanding, as well as clinical reasoning tasks. These models are lightweight enough to run on a single GPU and can be fine-tuned efficiently for specialized healthcare applications.
Graph of the Day
In a competition at MIT, eight teams of mathematicians competed against the AI model o4-mini-medium to answer the question of whether AI is already superhuman in the field of FrontierMath (advanced mathematics) - i.e. better than humans.
The model beat six out of eight teams. Only two human teams were better. Although AI is not yet clearly superior, it is close to reaching this milestone.
SW033291 protects the blood-brain barrier
Case Western researchers administered the 15-PGDH inhibitor SW033291 to Alzheimer's mice and prevented blood-brain barrier leakage, neurodegeneration and memory loss - all without amyloid targeting. This proof-of-concept opens up a new class of drugs for Alzheimer's disease, traumatic brain injury and age-related BBB damage and could substantially extend healthy life years.
Spatio-temporal patterns of active epigenetic turnover
A team led by Olmeda models DNA methylation cycles as synchronized oscillations for the first time and shows that genome-wide “clock domains” are formed, the size of which determines chromatin heterogeneity. This creates a controllable lever with which cells could fine-tune their epigenetic clock - and thus ageing processes - opening up new targets for rejuvenation through partial reprogramming.
Age-stratified clustering of multiple long-term conditions
From 570,000 British e-health records, a latent class analysis extracts 600 multimorbidity patterns across twelve five-year cohorts; 263 clusters are strictly age-specific, only 79 are repeated across generations. This shows that prevention and therapy must be designed to be life-stage sensitive - a data-driven step towards truly personalized longevity medicine.
Question of the Day
Will we beat cancer in the next 5 years?
Quote of the Day
